Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1240934

CC1=C([Si](C)(C)C2=C(C)c3cccc4cccc2c34)c2cccc3cccc1c23.[Cl-].[Cl-].[Zr+2][C@@H]1C=Cc2ccccc21

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5352162 1.00 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1ATMHSD17B10
Hydrochloric Acid SCHEMBL6548637 0.90
Hydrochloric Acid SCHEMBL5949214 0.90
Hydrochloric Acid SCHEMBL6548263 0.88
SCHEMBL7142364 0.85 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL6890162 0.83
Hydrochloric Acid SCHEMBL6895311 0.78 MAPK1 (0.35) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL7946917 0.73 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1ATMHSD17B10
Hydrochloric Acid SCHEMBL812668 0.72 HTR2A (0.40) HSD17B10
SCHEMBL6890779 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632532-B1 SOLVENT DISPERSION OF COMPOSITE RESIN AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-12-05 EP disclosed
US-8507603-B2 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2013-08-13 US disclosed
US-20110054118-A1 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-03-03 US disclosed
US-7879950-B2 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-02-01 US disclosed
US-20070245929-A1 Solvent Dispersion of Composite Resin and Uses Thereof MITSUI CHEMICALS, INC. (JP) 2007-10-25 US disclosed
EP-1632532-A1 SOLVENT DISPERSION OF COMPOSITE RESIN AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2006-03-08 EP disclosed
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
EP-0697419-B2 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS INC (JP) 2004-12-01 EP disclosed
EP-0704461-B1 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-6043325-A RGANOALUMINUM OXY-COMPOUND HAVING A SPECIFIC MOLAR RATIO OF THE ALKYL GROUP TO THE ALUMINUM ATOM, A FINE PARTICLE CARRIER AND A TRANSITION METAL COMPOUND AND HAS A SPECIFIC BULK DENSITY AND A SPECIFIC FLUIDITY INDEX, MITSUI CHEMICALS, INC. (JP) 2000-03-28 US disclosed
EP-0930320-A1 ETHYLENE/ALPHA-OLEFIN COPOLYMERS, COMPOSITIONS, AND PROCESSES FOR THE PREPARATION OF THE COPOLYMERS AND THE COMPOSITIONS Mitsui Chemicals, Inc. (JP) 1999-07-21 EP disclosed
EP-0697419-B1 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS INC (JP) 1999-05-06 EP disclosed
EP-0704461-A2 Olefin polymerization catalyst and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-04-03 EP disclosed
EP-0697419-A1 Olefin polymerization catalyst and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-02-21 EP disclosed