Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252173 | 0.88 | CA1 (0.40) | MELKPTGS2MKNK1ADORA2AADORA2B | |
| SCHEMBL252527 | 0.83 | RIPK2 (0.41) | MELKMKNK1ADORA2AADORA2BADORA1 | |
| SCHEMBL253332 | 0.82 | SCN9A (0.44) | MELKMKNK1ADORA2AADORA2BADORA1 | |
| SCHEMBL10182300 | 0.81 | RIPK2 (0.40) | MKNK1ADORA2AADORA2BADORA1GRM4 | |
| SCHEMBL10233351 | 0.79 | RIPK2 (0.43) | MELKMKNK1ADORA2AADORA2BADORA1 | |
| SCHEMBL10182269 | 0.78 | MKNK1 (0.41) | MELKMKNK1ADORA2AADORA2BADORA1 | |
| SCHEMBL12410406 | 0.78 | CYP2A6 (0.42) | MKNK1ADORA2AADORA2BADORA1CYP2A6 | |
| SCHEMBL12410399 | 0.78 | MKNK1 (0.44) | MKNK1ADORA2AADORA2BADORA1CYP2A6 | |
| SCHEMBL251938 | 0.78 | ASIC3 (0.42) | MKNK1ADORA2AADORA2BADORA1CYP2A6 | |
| SCHEMBL12410569 | 0.78 | CYP2A6 (0.42) | MKNK1ADORA2AADORA2BADORA1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | MELK 2620/4885PTGS2 2097/4885MKNK1 2220/4885 |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | MELK 2620/4885PTGS2 2097/4885MKNK1 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.