Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245414 | 0.86 | PDE10A (0.46) | GRM4PDE10AMKNK1GRM5HTR2B | |
| SCHEMBL3923984 | 0.84 | GRM5 (0.60) | CYP2A6GRM4PDE10AMKNK1GRM5 | |
| SCHEMBL12410587 | 0.82 | CYP2A6 (0.56) | CYP2A6GRM4RIPK2HTR2BMTNR1A | |
| SCHEMBL5668065 | 0.81 | GRM4 (0.48) | GRM4PDE10AMKNK1GRM5HTR2B | |
| SCHEMBL8354922 | 0.81 | GRM5 (0.48) | GRM4PDE10AMKNK1GRM5MKNK2 | |
| SCHEMBL5662955 | 0.81 | GRM5 (0.51) | GRM4PDE10AMKNK1GRM5HTR2B | |
| SCHEMBL12410450 | 0.80 | MKNK1 (0.47) | CYP2A6GRM4MKNK1GRM5RIPK2 | |
| SCHEMBL12410565 | 0.80 | MELK (0.54) | CYP2A6GRM4MKNK1RIPK2HTR2B | |
| SCHEMBL12203764 | 0.79 | PDE10A (0.46) | GRM4PDE10AMKNK1GRM5 | |
| SCHEMBL5218758 | 0.78 | PDE10A (0.46) | GRM4PDE10AMKNK1GRM5MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | CYP2A6 256/4885GRM4 1196/4885PDE10A 418/4885 |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | CYP2A6 256/4885GRM4 1196/4885PDE10A 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.