Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863945 | 0.95 | KMT2A (0.58) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL5792985 | 0.93 | KMT2A (0.59) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL6863947 | 0.90 | KMT2A (0.53) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL28410126 | 0.90 | KMT2A (0.53) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL6866158 | 0.89 | KMT2A (0.55) | KMT2AHTTTP53TSHRHSD17B10 | |
| SCHEMBL12902938 | 0.88 | KMT2A (0.51) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL5792981 | 0.88 | KMT2A (0.54) | KMT2APRSS1PRSS2PRSS3HTT | |
| SCHEMBL1615177 | 0.87 | TP53 (0.64) | KMT2AHTTTP53TSHRMEN1 | |
| SCHEMBL7777446 | 0.87 | TP53 (0.64) | KMT2AHTTTP53TSHRMEN1 | |
| SCHEMBL622925 | 0.87 | TP53 (0.64) | KMT2AHTTTP53TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344175-B2 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| US-8344175-B2 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| US-8334393-B2 | Chiral compounds and liquid crystal compositions and polymer networks derived therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-18 | — | — | US | disclosed |
| US-8334393-B2 | Chiral compounds and liquid crystal compositions and polymer networks derived therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110163267-A1 | CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110163267-A1 | CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110114885-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110114885-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | US | disclosed |
| US-7914700-B2 | Liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7914700-B2 | Liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7879256-B2 | bis(meth)acrylates with esters linking mesogen to a flexible spacer and polymerizable (meth)acrylates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879256-B2 | bis(meth)acrylates with esters linking mesogen to a flexible spacer and polymerizable (meth)acrylates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | GOLDFINGER MARC B | 2007-11-22 | — | — | US | disclosed |
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | GOLDFINGER MARC B | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267599-A1 | Liquid crystal compositions and polymer networks derived therefrom | F2, CCNB1, CYP2F1 | KMT2A 3323/4885PRSS1 3250/4885PRSS2 2651/4885 |
| US-20110163267-A1 | CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | CCNB1, F2, CYP4F11 | KMT2A 3164/4885PRSS1 3871/4885PRSS2 3646/4885 |
| US-20110114885-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | THEM6, NOTUM, WEE1 | KMT2A 3862/4885PRSS1 4185/4885PRSS2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.