Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107393 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL2573120 | 0.87 | BLM (0.50) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL2982712 | 0.87 | BLM (0.50) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL6107394 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL1552723 | 0.87 | CA12 (0.50) | ALDH1A1CYP3A4AKT1ITGB3ITGA2B | |
| SCHEMBL1350805 | 0.87 | CA12 (0.50) | ALDH1A1CYP3A4AKT1ITGB3ITGA2B | |
| SCHEMBL1350802 | 0.87 | CA12 (0.50) | ALDH1A1CYP3A4AKT1ITGB3ITGA2B | |
| SCHEMBL13269823 | 0.86 | CTSS (0.50) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL10290105 | 0.86 | CTSS (0.50) | KDM4EALDH1A1LMNACYP1A2POLB | |
| SCHEMBL20338607 | 0.86 | CTSS (0.50) | KDM4EALDH1A1LMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884204-B2 | such as (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-3-quinolinyl)phenyl]propionic acid, used for the teratment of inflammatory diseases, arthritis, inflammatory bowel diseases, lupus, multiple syndrome, asthma, psoriasis, allergies, diabetes and cardiovascular diseases | AJINOMOTO CO., INC. (JP) | 2011-02-08 | — | — | US | disclosed |