SCHEMBL1350802

SCHEMBL1350802

CC(C)(C)OC(=O)N[C@@](C)(Cc1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ENPEP Q07075 2/20 0.48
AKT1 P31749 3/20 0.48
CTSS P25774 4/20 0.47
CTSK P43235 2/20 0.47
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
TACR3 P29371 1/20 0.46
PPARA Q07869 2/20 0.46
PPARG P37231 1/20 0.46
ATM Q13315 1/20 0.46
ACE P12821 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
IDO1 P14902 1/20 0.45
ALDH1A1 P00352 2/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552723 1.00 CA12 (0.50) CA12CA1CA7CA14ENPEP
SCHEMBL1350805 1.00 CA12 (0.50) CA12CA1CA7CA14ENPEP
SCHEMBL7857502 0.91 CTSS (0.52) CA12CA1CA7CA14ENPEP
SCHEMBL2210451 0.89 CA12 (0.49) CA12CA1CA7CA14AKT1
SCHEMBL2210445 0.89 CA12 (0.49) CA12CA1CA7CA14AKT1
SCHEMBL3350999 0.88 ITGB3 (0.55) PPARAPPARGITGB3ITGA2B
SCHEMBL2573120 0.88 BLM (0.50) CA12CA1CA7CA14CTSS
SCHEMBL2024317 0.88 CA12 (0.48) CA12CA1CA7CA14ENPEP
SCHEMBL8278320 0.88 CA12 (0.48) CA12CA1CA7CA14ENPEP
SCHEMBL6107393 0.88 KDM4E (0.43) CA12CA1CA7CA14ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-20240057599-A1 METHODS FOR IMPROVING FRUIT QUALITY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2024-02-22 US disclosed
US-11812746-B2 Method of controlling fungal infections in plants THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2023-11-14 US disclosed
US-20200383327-A1 METHOD OF IMPROVING PLANT PERFORMANCE THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2020-12-10 US disclosed
US-20190246639-A1 METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCHORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2019-08-15 US disclosed
US-20180186860-A1 SYNTHETIC APOLIPOPROTEINS, AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR NANOLIPOPROTEIN PARTICLES FORMATION U.S. DEPARTMENT OF ENERGY 2018-07-05 US disclosed
EP-3006449-B1 METHOD FOR SYNTHESIZING OPTICALLY ACTIVE ALPHA-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[C,E]AZEPIN-6-YL]ACETAMIDE COMPOUND AND AMINO ACID HAMARI CHEMICALS LTD (JP) 2018-01-31 EP disclosed
US-9695112-B2 Method for synthesizing optically active α-amino acid using chiral metal complex comprising axially chiral N-(2-acylaryl)-2-[5,7-dihydro-6H-dibenzo[c,e]azepin-6-yl] acetamide compound and amino acid HAMARI CHEMICALS, LTD. (JP) 2017-07-04 US disclosed
US-9695112-B2 Method for synthesizing optically active α-amino acid using chiral metal complex comprising axially chiral N-(2-acylaryl)-2-[5,7-dihydro-6H-dibenzo[c,e]azepin-6-yl] acetamide compound and amino acid HAMARI CHEMICALS, LTD. (JP) 2017-07-04 US disclosed
WO-2017044899-A1 SYNTHETIC APOLIPOPROTEINS, AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR NANOLIPOPROTEIN PARTICLES FORMATION LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2017-03-16 WO disclosed
EP-0668770-A1 $g(a)-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY WARNER-LAMBERT COMPANY (US) 1995-08-30 EP disclosed
US-5386011-A Antiinflammatory agents; also, peptidomimetic compounds, i,e., agonists, having immunoregulatory effect against infections and cancer ABBOTT LABORATORIES (US) 1995-01-31 US disclosed
WO-1994009031-A1 ANALOGUES OF CHOLECYSTOKININ (30-33) CONTAINING AN ALPHA-SUBSTITUTED AMINOACID WARNER-LAMBERT COMPANY (US) 1994-04-28 WO disclosed
WO-1992019254-A1 α-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY WARNER-LAMBERT COMPANY (US) 1992-11-12 WO disclosed
WO-1992011858-A1 HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 1992-07-23 WO disclosed
EP-0074787-B1 RENALLY ACTIVE DIPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1985-03-27 EP disclosed
US-4448972-A Adamantyl containing intermediates SMITHKLINE BECKMAN CORPORATION (US) 1984-05-15 US disclosed
US-4395401-A Renally active dipeptides SMITHKLINE BECKMAN CORPORATION (US) 1983-07-26 US disclosed
US-4387049-A Adamantyl containing peptides SMITHKLINE BECKMAN CORPORATION (US) 1983-06-07 US disclosed
EP-0074787-A1 Renally active dipeptides SMITHKLINE BECKMAN CORPORATION (US) 1983-03-23 EP disclosed