Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20072963 | 0.88 | MGLL (0.56) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL3623634 | 0.86 | MGLL (0.59) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL18372942 | 0.85 | MGLL (0.61) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL28871457 | 0.85 | MGLL (0.61) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL3482800 | 0.80 | MGLL (0.54) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL11128738 | 0.78 | MGLL (0.52) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL1535503 | 0.78 | GAA (0.42) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL8168349 | 0.78 | MGLL (0.46) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL4418973 | 0.77 | GABBR2 (0.35) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL22544689 | 0.77 | MGLL (0.50) | MGLLFAAHALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493609-B2 | N-maleimidyl polymer derivatives | NEKTAR THERAPEUTICS (US) | 2016-11-15 | — | — | US | disclosed |
| US-20160083514-A1 | N-MALEIMIDYL POLYMER DERIVATIVES | NEKTAR THERAPEUTICS | 2016-03-24 | — | — | US | disclosed |
| US-9169350-B2 | N-maleimidyl polymer derivatives | NEKTAR THERAPEUTICS (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150166725-A1 | N-Maleimidyl Polymer Derivatives | NEKTAR THERAPEUTICS (US) | 2015-06-18 | — | — | US | disclosed |
| US-8992902-B2 | N-maleimidyl polymer derivatives | NEKTAR THERAPEUTICS (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140256957-A1 | N-Maleimidyl Polymer Derivatives | NEKTAR THERAPEUTICS (US) | 2014-09-11 | — | — | US | disclosed |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | MGLL 4175/4885FAAH 4134/4885ALDH1A1 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.