Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXO1 | Q12778 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 10/20 | 0.33 |
| ▸ | CNR1 | P21554 | 9/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4116045 | 0.88 | FOXO1 (0.46) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL27656225 | 0.84 | FOXO1 (0.42) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL27656227 | 0.83 | FOXO1 (0.44) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL17387389 | 0.79 | FOXO1 (0.59) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL31372321 | 0.79 | FOXO1 (0.59) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL18925604 | 0.78 | FOXO1 (0.51) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL1242497 | 0.76 | MEN1 (0.54) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL27635118 | 0.76 | MEN1 (0.54) | FOXO1MEN1GAAKMT2APDE10A | |
| SCHEMBL1243848 | 0.76 | FOXO1 (0.58) | FOXO1MEN1GAAKMT2ACNR2 | |
| SCHEMBL1243323 | 0.74 | MEN1 (0.75) | FOXO1MEN1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879878-B2 | such as {2-[({[7-(cyclohexylamino)-6-fluoro-4-oxo-1-[(3S)-tetrahydrofuran-3-yl]-1,4-dihydroquinolin-3-yl}carbonyl)amino]ethyl}phosphonic acid, used as platelet aggregation inhibitor and purinergic receptor (P2Y12) inhibitors; therapy for circulatory diseases involving thrombosis via platelet aggregation | ASTELLAS PHARMA INC. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1650192-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2006-04-26 | — | — | EP | disclosed |