Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272090 | 0.89 | KMT2A (0.64) | SMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL1269684 | 0.88 | CYP3A4 (0.67) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL5970008 | 0.88 | ALDH1A1 (0.62) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL2584810 | 0.88 | ALDH1A1 (0.62) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL7459479 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL12415397 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL26660431 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL12415402 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL18820798 | 0.80 | ALDH1A1 (0.72) | SMN1; SMN2L3MBTL1ALDH1A1HSD17B10KMT2A | |
| Isophthalic Acid SCHEMBL27639823 | 0.79 | KMT2A (0.55) | SMN1; SMN2L3MBTL1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172236-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CHAKRAVARTY PRASUN K | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172236-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | TRPV1, TRPA1, CACNA1D | SMN1; SMN2 365/4885L3MBTL1 4377/4885ALDH1A1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.