Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377718 | 0.88 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL12415468 | 0.80 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL17199293 | 0.80 | CYP1A2 (0.54) | ALDH1A1POLBMAPT | |
| SCHEMBL12377719 | 0.78 | TDP1 (0.43) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL12377714 | 0.72 | MEN1 (0.43) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL23855076 | 0.72 | NQO2 (0.56) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL35210324 | 0.72 | NQO2 (0.56) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10438855 | 0.72 | CYP4F2 (0.58) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL19400976 | 0.71 | KMT2A (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL17199107 | 0.71 | HDAC3 (0.48) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |