Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377717 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL12415465 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL28022240 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL10438855 | 0.79 | CYP4F2 (0.58) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL17199096 | 0.76 | CYP1A2 (0.63) | KDM4EALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL24276933 | 0.76 | HDAC6 (0.46) | ALDH1A1SMN1; SMN2ALOX15MAPTNPSR1 | |
| SCHEMBL30498970 | 0.75 | CDYL (0.60) | KDM4EALDH1A1HPGDNQO2MTNR1A | |
| SCHEMBL6615856 | 0.75 | CDYL (0.60) | KDM4EALDH1A1HPGDNQO2MTNR1A | |
| SCHEMBL31536704 | 0.75 | MAPT (0.51) | ALDH1A1SMN1; SMN2ALOX15RXFP1KMT2A | |
| SCHEMBL6274670 | 0.75 | MAPT (0.51) | ALDH1A1SMN1; SMN2ALOX15RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| WO-2009118157-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |