Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 7/20 | 0.59 |
| ▸ | AURKA | O14965 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 8/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.59 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 9/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.58 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.52 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.52 |
| ▸ | KIF5B | P33176 | 1/20 | 0.52 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190156 | 0.85 | AURKB (0.71) | AURKBAURKAKDREGFRMAPK14 | |
| SCHEMBL2189831 | 0.78 | AURKB (0.71) | AURKBAURKAKDREGFRMAPK14 | |
| SCHEMBL18158156 | 0.77 | AURKB (0.80) | AURKBAURKAKDREGFRMAPK14 | |
| SCHEMBL2195995 | 0.76 | EGFR (0.78) | AURKBAURKAKDREGFRRET | |
| SCHEMBL2192340 | 0.76 | EGFR (0.78) | AURKBAURKAKDREGFRRET | |
| Hydrochloric Acid SCHEMBL8809205 | 0.76 | AURKB (0.78) | AURKBAURKAKDREGFRMAPK14 | |
| Anilinoquinazoline1 SCHEMBL30195580 | 0.75 | AURKB (1.00) | AURKBAURKAKDREGFRMAPK14 | |
| Anilinoquinazoline1 SCHEMBL1066538 | 0.75 | AURKB (1.00) | AURKBAURKAKDREGFRMAPK14 | |
| SCHEMBL3947988 | 0.74 | AURKB (0.71) | AURKBAURKAKDREGFRMAPK14 | |
| SCHEMBL906972 | 0.74 | EPHA2 (1.00) | KDREPHA2EPHB4EGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172241-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110172241-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172241-A1 | Benzazole analogues and uses thereof | CYP3A5, CYP3A7, CYP3A43 | AURKB 1348/4885AURKA 1705/4885KDR 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.