SCHEMBL1241584

SCHEMBL1241584

COCCOc1ccsc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35
MAOA P21397 1/20 0.35
DYRK1A Q13627 1/20 0.35
FYN P06241 1/20 0.34
LTA4H P09960 3/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
P2RX3 P56373 1/20 0.33
PPARA Q07869 1/20 0.33
HPGD P15428 1/20 0.33
PKM P14618 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479449 0.94 KDM4E (0.42) KDM4ERECQLMAOADYRK1AFYN
SCHEMBL479245 0.94 KDM4E (0.42) KDM4ERECQLMAOADYRK1AFYN
SCHEMBL589611 0.94 KDM4E (0.42) KDM4ERECQLMAOADYRK1AFYN
Acetic Acid SCHEMBL28568167 0.89 PPARA (0.39) FYNLTA4HTSHRMAPTP2RX3
SCHEMBL27980027 0.89 LTA4H (0.38) KDM4ELTA4HCYP2A6PPARAHPGD
SCHEMBL4353502 0.81
SCHEMBL151357 0.79 CYP3A4 (0.48) LTA4HTSHR
SCHEMBL14897885 0.79 RARB (0.36) KDM4ERECQLLTA4HTSHRMAPT
SCHEMBL18411083 0.79 RARB (0.36) KDM4ERECQLLTA4HTSHRMAPT
SCHEMBL9691547 0.78 NR5A1 (0.48) LTA4HTSHRMAPTHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534883-B Antistatic latex glove and preparation method thereof 广州双一乳胶制品有限公司 2024-04-16 CN claimed
CN-117534883-A Antistatic latex glove and preparation method thereof 广州双一乳胶制品有限公司 2024-02-09 CN claimed
EP-0253594-A2 Polymerisable thiophene monomers, their production and polymers prepared therefrom COOKSON GROUP plc (GB) 1988-01-20 EP claimed
CN-118620186-A Organic conjugated polymer, preparation method thereof and zinc ion battery 大湾区大学(筹) 2024-09-10 CN disclosed
CN-117534883-B Antistatic latex glove and preparation method thereof 广州双一乳胶制品有限公司 2024-04-16 CN disclosed
CN-117534883-A Antistatic latex glove and preparation method thereof 广州双一乳胶制品有限公司 2024-02-09 CN disclosed
CN-106588899-B 6- oxaspiro [4.5] decane analog derivative, preparation method and its application in medicine that pyridyl group replaces 江苏恒瑞医药股份有限公司 2019-11-15 CN disclosed
CN-106588899-A Pyridyl-substituted 6-oxaspiro[4.5]decane derivative and preparation method thereof, and applications of pyridyl-substituted 6-oxaspiro[4.5]decane derivative in medicines 江苏恒瑞医药股份有限公司 2017-04-26 CN disclosed
US-7884107-B2 Human Double Minute 2 (HDM2) protein inhibitors; anticancer agents MERCK (US) 2011-02-08 US disclosed
US-7884107-B2 Human Double Minute 2 (HDM2) protein inhibitors; anticancer agents MERCK (US) 2011-02-08 US disclosed
US-7884107-B2 Human Double Minute 2 (HDM2) protein inhibitors; anticancer agents MERCK (US) 2011-02-08 US disclosed
EP-0328984-A1 Process for the preparaton of thiophene ethers HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP disclosed
EP-0328981-A2 Electrically conducting coating compound, process for its preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP disclosed
CN-1032799-A Improved conductive polymers HOECHST AG (DE) 1989-05-10 CN disclosed
EP-0313998-A2 Modified electrical conductive polymers HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-03 EP disclosed
CN-88103082-A Conductive coating compound, its manufacture method and application 1988-12-14 CN disclosed
EP-0292905-A2 Electrically conductive coating composition, method for its manufacture and its use HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-30 EP disclosed
CN-87105806-A Soluble conductive polymer, preparation method and application thereof 1988-05-04 CN disclosed
EP-0257573-A1 Soluble electrically conductive polymers, method of producing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-02 EP disclosed
EP-0253594-A2 Polymerisable thiophene monomers, their production and polymers prepared therefrom COOKSON GROUP plc (GB) 1988-01-20 EP disclosed