SCHEMBL479245

SCHEMBL479245

COCCOCCOCCOc1ccsc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
RECQL P46063 1/20 0.42
MAOA P21397 1/20 0.35
DYRK1A Q13627 1/20 0.35
CHEK1 O14757 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 1/20 0.35
APP P05067 3/20 0.35
FYN P06241 1/20 0.32
TSHR P16473 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LTA4H P09960 1/20 0.32
P2RX3 P56373 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479449 1.00 KDM4E (0.42) KDM4ERECQLMAOADYRK1ACHEK1
SCHEMBL589611 1.00 KDM4E (0.42) KDM4ERECQLMAOADYRK1ACHEK1
SCHEMBL1241584 0.94 KDM4E (0.35) KDM4ERECQLMAOADYRK1AFYN
SCHEMBL14897885 0.85 RARB (0.36) KDM4ERECQLTDP1MAPK1TSHR
SCHEMBL18411083 0.85 RARB (0.36) KDM4ERECQLTDP1MAPK1TSHR
Acetic Acid SCHEMBL28568167 0.84 PPARA (0.39) CHEK1FYNTSHRL3MBTL1LTA4H
SCHEMBL27980027 0.84 LTA4H (0.38) KDM4ETDP1MAPK1L3MBTL1LTA4H
SCHEMBL14854543 0.82 RARB (0.48) KDM4ERECQLTDP1MAPK1TSHR
SCHEMBL15412643 0.82 RARB (0.48) KDM4ERECQLTDP1MAPK1TSHR
SCHEMBL202344 0.82 HRH2 (0.44) KDM4ERECQLCHEK1LTA4HP2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110218298-B Soluble thiophene copolymer and preparation method and application thereof 华东师范大学 2021-12-24 CN disclosed
CN-110218298-A A kind of solubility thiophene copolymers and its preparation method and application 华东师范大学 2019-09-10 CN disclosed
WO-2017190345-A1 MOLECULAR FLUOROPHORES AND PREPARATION METHOD THEREOF AND USE FOR SHORT WAVELENGTH INFRARED IMAGING SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2017-11-09 WO disclosed
US-20120119154-A1 Electroconductive Coating Composition And Process For Production Of Electroconductive Coating Film SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-17 US disclosed
EP-2412770-A1 ELECTROCONDUCTIVE COATING COMPOSITION AND PROCESS FOR PRODUCTION OF ELECTROCONDUCTIVE COATING FILM Sanyo Chemical Industries, Ltd. (JP) 2012-02-01 EP disclosed
US-4992559-A Electrochromic displays, antistatic agents, pH detectors, electrodes COOKSON GROUP PLC (GB) 1991-02-12 US disclosed
EP-0253594-A2 Polymerisable thiophene monomers, their production and polymers prepared therefrom COOKSON GROUP plc (GB) 1988-01-20 EP disclosed