Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294273 | 0.88 | TLR8 (0.38) | TLR8HDAC1HDAC8ALDH1A1GLA | |
| SCHEMBL294272 | 0.88 | TLR8 (0.38) | TLR8HDAC1HDAC8ALDH1A1GLA | |
| SCHEMBL5748128 | 0.73 | CYP2A6 (0.39) | ALDH1A1 | |
| SCHEMBL7790790 | 0.73 | ALDH1A1 (0.37) | ALDH1A1RELA | |
| SCHEMBL28422917 | 0.72 | TLR8 (0.32) | TLR8 | |
| SCHEMBL28424989 | 0.70 | TLR8 (0.33) | TLR8 | |
| SCHEMBL8625941 | 0.70 | CNR1 (0.39) | — | |
| Anthracene SCHEMBL28105538 | 0.69 | TLR8 (0.47) | TLR8RELA | |
| SCHEMBL5748073 | 0.69 | CYP1A2 (0.53) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29084182 | 0.69 | HDAC1 (0.56) | HDAC1HDAC8ALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-B9 | HETEROCYCLIC COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-01-18 | — | — | EP | disclosed |
| EP-1919907-B1 | HETEROCYCLIC COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2011-02-23 | — | — | EP | disclosed |