SCHEMBL7790790

SCHEMBL7790790

C=Cc1ccc2ccc[c]c2c1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.33
TRPA1 O75762 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793747 0.85 ALDH1A1 (0.37) ALDH1A1TP53TDP1TSHRTRPA1
SCHEMBL5748128 0.81 CYP2A6 (0.39) ALDH1A1TDP1TSHR
SCHEMBL1241635 0.73 TLR8 (0.38) ALDH1A1RELA
SCHEMBL2318612 0.73 ESR1 (0.35) ALDH1A1TDP1
SCHEMBL756551 0.71 CYP2A6 (0.32)
SCHEMBL2257839 0.71 CYP3A4 (0.50) ALDH1A1TP53TDP1TSHR
SCHEMBL29357489 0.70 RELA (0.58) ALDH1A1TP53TDP1TSHRRELA
SCHEMBL2997515 0.70 RELA (0.58) ALDH1A1TP53TDP1TSHRRELA
SCHEMBL110160 0.70 RELA (0.58) ALDH1A1TP53TDP1TSHRRELA
SCHEMBL644725 0.69 CYP2A6 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed