SCHEMBL12416696

SCHEMBL12416696

CCCCOC(=O)/C=C/c1ccc(/N=C/c2ccc(OC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
TDP1 Q9NUW8 2/20 0.57
APP P05067 5/20 0.54
S100B P04271 1/20 0.52
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48
GSK3B P49841 1/20 0.48
PTGS2 P35354 2/20 0.47
PTGS1 P23219 1/20 0.47
CA12 O43570 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
F3 P13726 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518957 1.00 LMNA (0.60) LMNASMN1; SMN2TDP1APPS100B
SCHEMBL19460295 1.00 LMNA (0.60) LMNASMN1; SMN2TDP1APPS100B
SCHEMBL2451638 0.89 CA12 (0.56) LMNASMN1; SMN2TDP1S100BGSK3B
SCHEMBL2451637 0.89 CA12 (0.56) LMNASMN1; SMN2TDP1S100BGSK3B
SCHEMBL2451632 0.89 CA12 (0.56) LMNASMN1; SMN2TDP1S100BGSK3B
SCHEMBL4623831 0.89 LMNA (0.73) LMNASMN1; SMN2TDP1APPTAS1R3
SCHEMBL1614879 0.89 LMNA (0.73) LMNASMN1; SMN2TDP1APPTAS1R3
SCHEMBL1614553 0.86 LMNA (0.70) LMNASMN1; SMN2TDP1APPTAS1R3
SCHEMBL1614552 0.86 LMNA (0.70) LMNASMN1; SMN2TDP1APPTAS1R3
SCHEMBL59457 0.85 LMNA (0.68) LMNASMN1; SMN2TDP1APPTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3469576-B1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
US-10565925-B2 Full color display with intrinsic transparency SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-18 US disclosed
US-10554962-B2 Multi-layer high transparency display for light field generation SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-04 US disclosed
US-10453371-B2 Multi-layer display with color and contrast enhancement SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-22 US disclosed
US-10375365-B2 Projection system with enhanced color and contrast SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-06 US disclosed
EP-3479163-A1 MULTI-LAYER HIGH TRANSPARENCY DISPLAY FOR LIGHT FIELD GENERATION Samsung Electronics Co., Ltd. (KR) 2019-05-08 EP disclosed
EP-3469791-A1 PROJECTION SYSTEM WITH ENHANCED COLOR AND CONTRAST Samsung Electronics Co., Ltd. (KR) 2019-04-17 EP disclosed
EP-3469576-A1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT Samsung Electronics Co., Ltd. (KR) 2019-04-17 EP disclosed
EP-3455845-A1 FULL COLOR DISPLAY WITH INTRINSIC TRANSPARENCY Samsung Electronics Co., Ltd. (KR) 2019-03-20 EP disclosed
US-20170310940-A1 PROJECTION SYSTEM WITH ENHANCED COLOR AND CONTRAST SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-26 US disclosed
US-20170309215-A1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-26 US disclosed
US-20170310956-A1 MULTI-LAYER HIGH TRANSPARENCY DISPLAY FOR LIGHT FIELD GENERATION SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-26 US disclosed
US-20170301288-A1 FULL COLOR DISPLAY WITH INTRINSIC TRANSPARENCY SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-19 US disclosed
US-20110172234-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-07-14 US disclosed
US-20110172234-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-07-14 US disclosed
US-7915245-B2 Using small molecules as binding ligands, for the recruitment of Fas-associated death domain protein, activation of death-inducing signaling complex, caspase-8, and apoptosis in malignant cells; anticarcinogens, antitumor agents; enhanced cellular differentiation, minimizing cytolysis to healthy cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-03-29 US disclosed
US-7915245-B2 Using small molecules as binding ligands, for the recruitment of Fas-associated death domain protein, activation of death-inducing signaling complex, caspase-8, and apoptosis in malignant cells; anticarcinogens, antitumor agents; enhanced cellular differentiation, minimizing cytolysis to healthy cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-03-29 US disclosed
US-20080214547-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS UNIVERSITY OF MARYLAND, BALTIMORE 2008-09-04 US disclosed
US-20080214547-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS UNIVERSITY OF MARYLAND, BALTIMORE 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214547-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS BID, BAD, MCL1 LMNA 947/4885SMN1; SMN2 1896/4885TDP1 2375/4885
US-20110172234-A1 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS BID, BAD, MCL1 LMNA 947/4885SMN1; SMN2 1896/4885TDP1 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.