SCHEMBL1614879

SCHEMBL1614879

CCCCOC(=O)C=Cc1ccc(OC)cc1

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TDP1 Q9NUW8 2/20 0.70
APP P05067 5/20 0.66
GSK3B P49841 1/20 0.59
F3 P13726 1/20 0.58
TAS1R3 Q7RTX0 1/20 0.57
TAS1R1 Q7RTX1 1/20 0.57
ATM Q13315 2/20 0.57
THRB P10828 1/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MAPT P10636 1/20 0.55
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4623831 1.00 LMNA (0.73) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL1614553 0.97 LMNA (0.70) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL1614552 0.97 LMNA (0.70) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL8872231 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL2489079 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL4070152 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL8872489 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL59457 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL30746 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B
SCHEMBL4070148 0.96 LMNA (0.68) LMNASMN1; SMN2TDP1APPGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115362290-B Liquid softener compositions 狮王株式会社 2025-01-24 CN disclosed
CN-115135307-B Cell delivery vehicle 株式会社ITO 2024-11-22 CN disclosed
EP-3348251-B1 SUNSCREEN COMPOSITIONS GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS US LLC (US) 2024-01-17 EP disclosed
WO-2023194511-A1 COMPOSITION FOR THE COSMETIC TREATMENT OF KERATIN FIBERS BIOSYNTHIS (FR) 2023-10-12 WO disclosed
CN-116334921-A Liquid softener compositions 狮王株式会社 2023-06-27 CN disclosed
CN-115362290-A Liquid softener composition 狮王株式会社 2022-11-18 CN disclosed
EP-3953407-A1 TWO-COMPONENT POLYURETHANE COATINGS HAVING IMPROVED POT LIFE WITHOUT A LOSS OF WEATHERING RESISTANCE Covestro Intellectual Property GmbH & Co. KG (DE) 2022-02-16 EP disclosed
EP-2909130-B1 CATALYSIS BY METAL NANOPARTICLES DISPERSED WITHIN A HIERARCHICALLY POROUS CARBON MATERIAL BAKKER MARTIN (US) 2022-01-26 EP disclosed
CN-106367212-B Liquid softener composition 狮王株式会社 2021-04-20 CN disclosed
EP-3797756-A1 SUNSCREEN AGENT USING CELLULOSE NANOFIBERS Nature Costech Co., Ltd. (KR) 2021-03-31 EP disclosed
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters GOLDSCHMIDT GMBH (DE) 2005-10-20 US disclosed
CN-1220723-C Method for decreasing dust deposit on polyolefin film CIBA SC HOLDING AG (CH) 2005-09-28 CN disclosed
US-6784295-B2 CARRIED OUT IN THE PRESENCE OF AN INORGANIC BASE OR ORGANIC NITROGEN BASE AND A PALLADIUM COMPLEX CATALYST CONTAINING SECONDARY MONOPHOSPHINES WITH ALIPHATIC, BRANCHED OR CYCLIC SUBSTITUENTS AS LIGANDS SOLVIAS AG (CH) 2004-08-31 US disclosed
CN-1151197-C Stable metallocene polyolefine �������⻯ѧƷ�ع����޹�˾ 2004-05-26 CN disclosed
EP-1132361-B1 Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds SOLVIAS AG (CH) 2003-05-14 EP disclosed
EP-1132361-A1 Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds Solvias AG (CH) 2001-09-12 EP disclosed
US-6194627-B1 REACTING HALOAROMATIC COMPOUND WITH OLEFIN IN PRESENCE OF PALLADIUM COMPOUND AS CATALYST AVENTIS RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) 2001-02-27 US disclosed
US-5698755-A Process for preparing aromatic olefins using palladacycle catalysis HOECHST AG (DE) 1997-12-16 US disclosed
CN-1121350-A Increasing the molecular weight of polyesters and premix useful for this process CIBA GEIGY AG (CH) 1996-04-24 CN disclosed
CN-1114653-A Oligomeric hals phophites and hals phosphonites as stabilisers CIBA GEIGY AG (CH) 1996-01-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters APP, BACE1, CBR1 LMNA 1320/4885SMN1; SMN2 4365/4885TDP1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.