Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030263 | 0.85 | AHCY (0.37) | AHCYTRPM2 | |
| SCHEMBL12418881 | 0.81 | EGFR (0.41) | AHCYTRPM2ADORA2ACA2CA4 | |
| SCHEMBL12418882 | 0.80 | AHCY (0.40) | AHCYADORA2ACA2CA4CA9 | |
| SCHEMBL12417901 | 0.80 | AHCY (0.40) | AHCYADORA2ACA2CA4CA9 | |
| SCHEMBL14030163 | 0.80 | AHCY (0.40) | AHCYTRPM2ADORA2ACA2CA4 | |
| SCHEMBL12418879 | 0.78 | AHCY (0.36) | AHCYTRPM2ADORA2ACA2CA4 | |
| SCHEMBL14034301 | 0.74 | AHCY (0.37) | AHCYADORA2ACA2CA4CA9 | |
| SCHEMBL14472999 | 0.73 | AHCY (0.60) | AHCYADORA2A | |
| SCHEMBL10284145 | 0.73 | AHCY (0.60) | AHCYADORA2A | |
| SCHEMBL12379179 | 0.72 | TRPM2 (0.58) | TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |