Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.58 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379202 | 1.00 | TRPM2 (0.58) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL12379200 | 0.85 | IMPDH2 (0.62) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL12379228 | 0.84 | TRPM2 (0.66) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL14520292 | 0.84 | TRPM2 (0.57) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL12379199 | 0.84 | IMPDH2 (0.61) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL12379201 | 0.83 | TRPM2 (0.56) | TRPM2IMPDH2IMPDH1 | |
| SCHEMBL7102573 | 0.83 | DPP4 (0.69) | — | |
| SCHEMBL12379181 | 0.82 | TRPM2 (0.58) | TRPM2 | |
| SCHEMBL22837892 | 0.82 | TRPM2 (0.58) | TRPM2 | |
| SCHEMBL22837893 | 0.82 | TRPM2 (0.58) | TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |