Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403609 | 0.79 | L3MBTL1 (0.67) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL10515336 | 0.77 | L3MBTL1 (0.65) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL3073197 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL14676586 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL298750 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL14890349 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL18784165 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL6567898 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL12378232 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1MAPTALOX15 | |
| SCHEMBL19491230 | 0.70 | L3MBTL1 (0.41) | KDM4EALDH1A1L3MBTL1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008287-B2 | Use treating HIV and AIDS; tricyclic compounds such as those based on 5-sulfonamido-9-hydroxy-6,8-dihydrdo-7H-pyrrolo[3,4-g]quinoline-8-one | GILEAD SCIENCES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20080058315-A1 | Integrase inhibitors | GILEAD SCIENCES, INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058315-A1 | Integrase inhibitors | TYMP, DNTT, PAICS | KDM4E 1971/4885ALDH1A1 2040/4885L3MBTL1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.