Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.57 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060485 | 0.83 | P4HTM (0.50) | P4HTMP4HA1KDM4EDBHGAA | |
| SCHEMBL25912786 | 0.82 | P4HTM (0.41) | P4HTMP4HA1KDM4EDBHGAA | |
| SCHEMBL14519853 | 0.82 | NAPRT (0.62) | KDM4EDBHGAARECQLNPC1 | |
| SCHEMBL30530049 | 0.82 | NAPRT (0.62) | KDM4EDBHGAARECQLNPC1 | |
| SCHEMBL8006507 | 0.82 | HDAC1 (0.56) | KDM4EDBHGAARECQLHCAR3 | |
| SCHEMBL24663641 | 0.81 | RXFP1 (0.71) | KDM4ELDHARXFP1NPC1RAB9A | |
| SCHEMBL25912773 | 0.81 | P4HTM (0.54) | P4HTMKDM4ELDHABAZ2BNPC1 | |
| SCHEMBL13890820 | 0.81 | ADORA3 (0.41) | P4HTMP4HA1KDM4EGAALDHA | |
| SCHEMBL5433303 | 0.80 | KDM4E (0.44) | P4HTMP4HA1KDM4EDBHGAA | |
| SCHEMBL13890796 | 0.80 | KDM4E (0.44) | P4HTMP4HA1KDM4EDBHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171171-A1 | BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171171-A1 | BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC7 | P4HTM 3705/4885P4HA1 2732/4885KDM4E 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.