SCHEMBL25912786

SCHEMBL25912786

CC(C)C(=O)c1ccc(-c2nnc(-c3ncccn3)nn2)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 4/20 0.41
P4HA1 P13674 2/20 0.40
LDHA P00338 1/20 0.38
TP53 P04637 1/20 0.38
BAZ2B Q9UIF8 1/20 0.37
KDM4E B2RXH2 2/20 0.37
DBH P09172 1/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.37
HPGDS O60760 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
RXFP1 Q9HBX9 2/20 0.33
ROCK2 O75116 1/20 0.33
PRKG1 Q13976 1/20 0.33
HCAR3 P49019 1/20 0.33
NPC1 O15118 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25912773 0.90 P4HTM (0.54) P4HTMLDHATP53BAZ2BKDM4E
SCHEMBL12418685 0.82 P4HTM (0.57) P4HTMP4HA1LDHABAZ2BKDM4E
SCHEMBL12348485 0.81 P4HTM (0.63) P4HTMP4HA1LDHATP53BAZ2B
SCHEMBL15748102 0.73 HPGDS (0.48) BAZ2BKDM4EGAAHPGDSNPC1
SCHEMBL13890820 0.72 ADORA3 (0.41) P4HTMP4HA1LDHAKDM4EGAA
SCHEMBL21553939 0.72 SMN1; SMN2 (0.49) KDM4EHPGDSL3MBTL1
SCHEMBL10060485 0.71 P4HTM (0.50) P4HTMP4HA1KDM4EDBHGAA
SCHEMBL25912779 0.71 TRPM8 (0.41) TP53KDM4EGAARECQLTRPM8
SCHEMBL15133134 0.71 HPGDS (0.48) P4HTMKDM4EHPGDSCYP1A2NPC1
SCHEMBL27001722 0.70 LDHA (0.62) P4HTMP4HA1LDHATP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX THE NOGUCHI INSTITUTE (JP) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX FCGRT, HBZ, FUT4 P4HTM 2951/4885P4HA1 3355/4885LDHA 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.