Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12392022 | 0.86 | NR1H4 (0.40) | ALDH1A1LMNAHPGDSMN1; SMN2NR1H4 | |
| SCHEMBL21206352 | 0.83 | TSHR (0.40) | KDM4EALDH1A1LMNASMN1; SMN2NR1H4 | |
| SCHEMBL25446383 | 0.80 | NR1H4 (0.38) | KDM5CKDM2AKDM3AALDH1A1LMNA | |
| SCHEMBL18307624 | 0.80 | GLA (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2GLA | |
| SCHEMBL6072289 | 0.79 | ALDH1A1 (0.45) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL23675961 | 0.79 | MAPK1 (0.37) | ALDH1A1LMNASMN1; SMN2NR1H4GLA | |
| SCHEMBL22623634 | 0.78 | ALDH1A1 (0.46) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL12417866 | 0.78 | KDM4E (0.42) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL26414505 | 0.77 | ALDH1A1 (0.34) | KDM5CKDM2AKDM3AALDH1A1LMNA | |
| SCHEMBL3279219 | 0.76 | MME (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | KDM4E 3925/4885KDM5C 4202/4885KDM4C 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.