Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071691 | 0.85 | L3MBTL1 (0.50) | ALDH1A1LMNAKDM5CDPP4HPGD | |
| SCHEMBL12417866 | 0.82 | KDM4E (0.42) | ALDH1A1LMNAKDM4EKDM5CKDM4C | |
| SCHEMBL6072137 | 0.82 | DPP4 (0.45) | ALDH1A1LMNAKDM5CDPP4L3MBTL1 | |
| SCHEMBL23130873 | 0.80 | SMPD1 (0.49) | KDM5CDPP4 | |
| SCHEMBL4134269 | 0.80 | DPP4 (0.43) | ALDH1A1LMNADPP4GLASCD | |
| SCHEMBL12418868 | 0.79 | KDM4E (0.40) | ALDH1A1LMNAKDM4EKDM5CKDM4C | |
| SCHEMBL7424494 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4EKDM5CKDM4C | |
| SCHEMBL19450894 | 0.79 | GLS (0.45) | KDM4EKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL20615682 | 0.79 | DPP4 (0.40) | ALDH1A1LMNADPP4HPGDSMN1; SMN2 | |
| SCHEMBL22062686 | 0.79 | DPP4 (0.46) | ALDH1A1LMNADPP4SCDCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120287-A | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-115087652-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115052873-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114787147-A | Heterocyclic compounds as modulators of interferon gene Stimulators (STING) | 雷沃医疗有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2019-11-26 | — | — | US | disclosed |
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2019-11-26 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2018-02-01 | — | — | US | disclosed |
| WO-2017072021-A1 | HETEROARYLCARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |
| US-20160016998-A1 | HIGH-AFFINITY MATRIPTASE INHIBITORS | MERCK PATENT GMBH (DE) | 2016-01-21 | — | — | US | disclosed |
| US-20160016998-A1 | HIGH-AFFINITY MATRIPTASE INHIBITORS | MERCK PATENT GMBH (DE) | 2016-01-21 | — | — | US | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | UNIVERSITÀ DI PISA (IT) | 2012-12-06 | — | — | US | disclosed |
| EP-1874739-B1 | PHARMACEUTICALLY ACTIVE DIAZEPANES | NOVARTIS AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | OBERHAUSER BERNDT | 2008-12-04 | — | — | US | disclosed |
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | OBERHAUSER BERNDT | 2008-12-04 | — | — | US | disclosed |
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | VCAM1, ICAM1, CD69 | ALDH1A1 137/4885LMNA 3812/4885KDM4E 2996/4885 |
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | ALDH1A1 1815/4885LMNA 4479/4885KDM4E 2874/4885 |
| US-20160016998-A1 | HIGH-AFFINITY MATRIPTASE INHIBITORS | MMP7, MATR3, TMPRSS15 | ALDH1A1 4072/4885LMNA 2335/4885KDM4E 1433/4885 |
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | LDHA, LDHB, DLD | ALDH1A1 84/4885LMNA 755/4885KDM4E 1327/4885 |
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | CLIC1, GRIK1, CA3 | ALDH1A1 1767/4885LMNA 1194/4885KDM4E 3017/4885 |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | CLIC1, GRIK1, CA3 | ALDH1A1 1767/4885LMNA 1194/4885KDM4E 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.