Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037286 | 0.81 | GRIK1 (0.34) | ALDH1A1GRIK1CPT2CPT1AGRIK2 | |
| SCHEMBL26778046 | 0.81 | GRIK1 (0.34) | ALDH1A1GRIK1CPT2CPT1AGRIK2 | |
| SCHEMBL18116107 | 0.81 | GRIK1 (0.38) | ALDH1A1TDP1GRIK1GRIK2MAPT | |
| SCHEMBL12420389 | 0.81 | GRIK1 (0.38) | ALDH1A1TDP1GRIK1GRIK2MAPT | |
| SCHEMBL10037299 | 0.81 | GRIK1 (0.34) | ALDH1A1GRIK1CPT2CPT1AGRIK2 | |
| SCHEMBL26754222 | 0.81 | GRIK1 (0.34) | ALDH1A1GRIK1CPT2CPT1AGRIK2 | |
| SCHEMBL15745571 | 0.80 | SLC1A1 (0.34) | ALDH1A1GRIK1MAPTPTGS1SLC7A5 | |
| SCHEMBL17085295 | 0.80 | SLC1A1 (0.34) | ALDH1A1GRIK1MAPTPTGS1SLC7A5 | |
| SCHEMBL17789294 | 0.80 | SLC1A1 (0.34) | ALDH1A1GRIK1MAPTPTGS1SLC7A5 | |
| SCHEMBL16602077 | 0.77 | GRIK1 (0.39) | ALDH1A1GRIK1GRIK2MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172193-A1 | PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172193-A1 | PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | ARFGAP1, ABCC1, FPR1 | ALDH1A1 335/4885TDP1 3566/4885GRIK1 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.