SCHEMBL12420685

SCHEMBL12420685

Cc1ccc(N2C(=O)c3ccc(C(=O)c4ccc5c(c4)C(=O)N(C)C5=O)cc3C2=O)cc1C

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.73
ALDH1A1 P00352 5/20 0.60
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 2/20 0.58
NPC1 O15118 1/20 0.58
MAPK1 P28482 1/20 0.58
CASP1 P29466 1/20 0.58
RAB9A P51151 1/20 0.58
HTT P42858 1/20 0.56
CA9 Q16790 5/20 0.50
CA1 P00915 4/20 0.50
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.47
CA4 P22748 2/20 0.47
APEX1 P27695 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905644 0.92 NPSR1 (0.62) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL15745965 0.88 NPSR1 (0.57) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL7593002 0.87 CA9 (0.65) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL17676353 0.86 NPSR1 (0.65) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL12891172 0.86 CA9 (0.63) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL10098940 0.84 CA9 (0.60) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL8276142 0.83 MAPK1 (0.58) NPSR1ALDH1A1MEN1KMT2AMAPK1
SCHEMBL10053398 0.82 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ATSHRAPEX1
SCHEMBL17327599 0.82 NPSR1 (0.50) NPSR1ALDH1A1MEN1KMT2ATSHR
SCHEMBL10098939 0.82 ALDH1A1 (0.59) NPSR1ALDH1A1MEN1KMT2ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170216778-A1 MEMBRANE MODULE MEMBRANE EXTRACTION TECHNOLOGY LTD. (GB) 2017-08-03 US disclosed
US-9308499-B1 Polyimide blend membranes for gas separations UOP LLC (US) 2016-04-12 US disclosed
US-9308487-B1 Polyimide blend membranes for gas separations UOP LLC (US) 2016-04-12 US disclosed
US-20110168627-A1 MEMBRANE MODULE MEMBRANE EXTRACTION TECHNOLOGY LTD. (GB) 2011-07-14 US disclosed