Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.68 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | PHGDH | O43175 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Debrisoquin SCHEMBL29390380 | 0.81 | TMPRSS2 (1.00) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL8244060 | 0.81 | NOTUM (0.68) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| Debrisoquin SCHEMBL309184 | 0.81 | TMPRSS2 (1.00) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL30539318 | 0.81 | NOTUM (1.00) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL3210469 | 0.81 | NOTUM (1.00) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL20749828 | 0.78 | NOTUM (0.64) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL5673815 | 0.78 | TMPRSS2 (0.64) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL4290600 | 0.77 | NOTUM (0.68) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL13497358 | 0.76 | TMPRSS2 (0.57) | MAOANOTUMTMPRSS2HTR1AADRA2A | |
| SCHEMBL27901981 | 0.76 | NOTUM (0.72) | MAOANOTUMTMPRSS2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788359-B1 | COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS | RES TRIANGLE INST (US) | 2017-03-01 | — | — | EP | disclosed |
| US-20110172416-A1 | AMIDINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172416-A1 | AMIDINE DERIVATIVE | SERPINC1, F12, F11 | MAOA 2233/4885NOTUM 1106/4885TMPRSS2 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.