Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478630 | 0.93 | CNR2 (0.61) | CNR2XDHPTGER1FFAR4KDM4E | |
| SCHEMBL15134602 | 0.86 | CNR2 (0.58) | CNR2PTGER1FFAR4CDK2CCNA2 | |
| SCHEMBL12420759 | 0.86 | CNR2 (0.46) | CNR2XDHPTGER1KDM4EALOX15 | |
| SCHEMBL15129078 | 0.85 | CNR2 (0.60) | CNR2PTGER1FFAR4TDP1CDK2 | |
| SCHEMBL15128998 | 0.85 | CNR2 (0.60) | CNR2PTGER1FFAR4TDP1CDK2 | |
| SCHEMBL15129404 | 0.83 | CNR2 (0.58) | CNR2PTGER1FFAR4CDK2CCNA2 | |
| SCHEMBL15129281 | 0.82 | CNR2 (0.54) | CNR2XDHPTGER1FFAR4CDK2 | |
| SCHEMBL15134605 | 0.82 | CNR2 (0.54) | CNR2XDHPTGER1FFAR4CDK2 | |
| SCHEMBL15129249 | 0.80 | CNR2 (0.52) | CNR2XDHPTGER1FFAR4CDK2 | |
| SCHEMBL18128987 | 0.78 | KDM4E (0.48) | CNR2FFAR4KDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | CNR2 134/4885XDH 419/4885PTGER1 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.