Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195616 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2193327 | 0.88 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL16623339 | 0.87 | NPC1 (0.74) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL1999354 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL1995023 | 0.86 | RAB9A (0.60) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2192968 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2194530 | 0.84 | NPC1 (0.70) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2194816 | 0.84 | NPC1 (0.70) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2194815 | 0.83 | NPC1 (0.65) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2195549 | 0.83 | NPC1 (0.65) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | SMN1; SMN2 1022/4885RAB9A 2622/4885NPC1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.