Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ILK | Q13418 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12422162 | 0.86 | MMP13 (0.63) | HTTSMN1; SMN2ILKALDH1A1CYP3A4 | |
| SCHEMBL10311768 | 0.83 | RORC (0.71) | HTTSMN1; SMN2PTPN1RORCALDH1A1 | |
| SCHEMBL2628245 | 0.81 | RORC (0.68) | HTTSMN1; SMN2PTPN1RORCALDH1A1 | |
| SCHEMBL12408910 | 0.79 | MAPT (0.59) | SMN1; SMN2RORCALDH1A1NPC1RAB9A | |
| SCHEMBL12422169 | 0.77 | MAPT (0.67) | SMN1; SMN2ILKALDH1A1TDP1NPC1 | |
| SCHEMBL1983034 | 0.77 | RORC (0.63) | HTTSMN1; SMN2PTPN1RORCALDH1A1 | |
| SCHEMBL1983033 | 0.77 | RORC (0.63) | HTTSMN1; SMN2PTPN1RORCALDH1A1 | |
| SCHEMBL12422008 | 0.76 | MAPT (0.59) | SMN1; SMN2RORCALDH1A1NPC1RAB9A | |
| SCHEMBL31591973 | 0.76 | RORC (0.59) | HTTSMN1; SMN2ILKPTPN1RORC | |
| SCHEMBL3201047 | 0.75 | APP (0.52) | HTTSMN1; SMN2ILKNPBWR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | HTT 8/4885SMN1; SMN2 1022/4885ILK 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.