Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE6D | O43924 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509708 | 1.00 | PKM (0.59) | PKMCA12CA1CA2CA9 | |
| SCHEMBL4401352 | 0.99 | PKM (0.60) | PKMCA12CA1CA2CA9 | |
| SCHEMBL16693779 | 0.99 | PKM (0.60) | PKMCA12CA1CA2CA9 | |
| SCHEMBL10168530 | 0.99 | PKM (0.60) | PKMCA12CA1CA2CA9 | |
| SCHEMBL12671591 | 0.91 | F2 (0.61) | PKMCA12CA1CA2CA9 | |
| SCHEMBL18677718 | 0.88 | PKM (0.49) | PKMCA12CA1CA2CA9 | |
| SCHEMBL997504 | 0.86 | F2 (0.67) | PKMCA12CA1CA2CA9 | |
| SCHEMBL1263500 | 0.85 | FOLH1 (0.47) | PKMCA12CA1CA2CA9 | |
| SCHEMBL26754234 | 0.85 | PRSS1 (0.65) | PKMCA12CA1CA2CA9 | |
| SCHEMBL31654083 | 0.85 | PRSS1 (0.65) | PKMCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171673-A1 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2011-07-14 | — | — | US | disclosed |