Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12423825 | 0.83 | KMT2A (0.51) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5473546 | 0.83 | KMT2A (0.56) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12423015 | 0.79 | KDM4E (0.65) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2931171 | 0.75 | KDM4E (0.71) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4371734 | 0.75 | PDGFRB (0.71) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13173589 | 0.74 | PLA2G4A (0.56) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL335235 | 0.73 | PDGFRB (0.79) | KMT2AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL4369016 | 0.73 | PLA2G4A (0.67) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1144832 | 0.73 | KDM4E (0.65) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12422884 | 0.73 | KDM4E (0.62) | KMT2AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103559-A1 | OLIGOMER MODIFIED DIAROMATIC SUBSTITUTED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2011-08-25 | — | — | WO | disclosed |