SCHEMBL12423368

SCHEMBL12423368

OCCc1ccsc1-c1ccc(-c2sccc2CCO)s1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.34
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174119 0.85 TP53 (0.34) KMT2ATP53ALOX15MAPK1
SCHEMBL31098181 0.84 DPP4 (0.44) DPP4KMT2AALDH1A1MAPTHPGD
SCHEMBL5171835 0.82 DPP4 (0.41) DPP4KMT2AMEN1ALDH1A1GLA
SCHEMBL14646142 0.80 TAAR1 (0.36)
SCHEMBL12913153 0.77 TYR (0.34) ALDH1A1
SCHEMBL15972026 0.75 NEK2 (0.34) DPP4KMT2AALDH1A1TP53ALOX15
SCHEMBL1408548 0.74 TP53 (0.54) KMT2AALDH1A1HPGDTP53ALOX15
SCHEMBL1828118 0.74 LIPG (0.39) KMT2AMEN1ALDH1A1MAPTTP53
SCHEMBL8586027 0.74 DPP4 (0.57) DPP4KMT2AMEN1ALDH1A1GLA
SCHEMBL16697972 0.74 LIPG (0.39) KMT2AMEN1ALDH1A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2817304-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BioChromix NewCo AB (SE) 2014-12-31 EP claimed
WO-2013009259-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB (SE) 2013-01-17 WO claimed
US-9359311-B2 Substituted aromatic oligomers NEUROSCIOS GMBH (AT) 2016-06-07 US disclosed
US-9359311-B2 Substituted aromatic oligomers NEUROSCIOS GMBH (AT) 2016-06-07 US disclosed
US-9359311-B2 Substituted aromatic oligomers NEUROSCIOS GMBH (AT) 2016-06-07 US disclosed
US-9012656-B2 Oligothiophene derivate as molecular probes CELLUMINOVA AB (SE) 2015-04-21 US disclosed
US-9012656-B2 Oligothiophene derivate as molecular probes CELLUMINOVA AB (SE) 2015-04-21 US disclosed
EP-2536712-B1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES CELLUMINOVA AB (SE) 2015-03-18 EP disclosed
EP-2817304-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BioChromix NewCo AB (SE) 2014-12-31 EP disclosed
US-20140135322-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB 2014-05-15 US disclosed
US-20140135322-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB 2014-05-15 US disclosed
US-20140135322-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB 2014-05-15 US disclosed
WO-2013036196-A1 NOVEL THIOPHENE COMPOUNDS AND METHOD FOR IN VIVO IMAGING BIOCHROMIX AB (SE) 2013-03-14 WO disclosed
WO-2013009259-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB (SE) 2013-01-17 WO disclosed
WO-2013009259-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY BIOCHROMIX PHARMA AB (SE) 2013-01-17 WO disclosed
US-20120315646-A1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES CELLUMINOVA AB (SE) 2012-12-13 US disclosed
US-20120315646-A1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES CELLUMINOVA AB (SE) 2012-12-13 US disclosed
WO-2011102789-A1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES OBOE IPR AB (SE) 2011-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135322-A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY PRNP, TBCA, HSPA5 DPP4 4095/4885KMT2A 4329/4885MEN1 2047/4885
US-20120315646-A1 OLIGOTHIOPHENE DERIVATE AS MOLECULAR PROBES NMT1, DNTT, NOTCH4 DPP4 1879/4885KMT2A 1291/4885MEN1 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.