Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909691 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| SCHEMBL7039277 | 0.88 | GAA (0.61) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| SCHEMBL2371651 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL30539159 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL836536 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL33664 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL27405553 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRMAPTHTT | |
| SCHEMBL2862890 | 0.80 | RAB9A (0.50) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| SCHEMBL31557927 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| Methyl Alcohol SCHEMBL28251314 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |