Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197781 | 0.91 | KCNA5 (0.45) | GAAATMCYP3A4KCNA5NPC1 | |
| SCHEMBL2194938 | 0.87 | SMN1; SMN2 (0.42) | ATMCYP3A4KCNA5NPC1RAB9A | |
| SCHEMBL2198569 | 0.86 | BRD4 (0.40) | GAAATMCYP3A4PDE10AKCNA5 | |
| SCHEMBL2198613 | 0.86 | NPC1 (0.41) | ATMCYP3A4PDE10AKCNA5NPC1 | |
| SCHEMBL2198005 | 0.86 | HSD11B1 (0.40) | ATMCYP3A4KCNA5NPC1RAB9A | |
| SCHEMBL2195309 | 0.84 | KCNA5 (0.45) | ATMCYP3A4KCNA5NPC1RAB9A | |
| SCHEMBL2197442 | 0.83 | NPC1 (0.41) | GAAATMCYP3A4PDE10AKCNA5 | |
| SCHEMBL2200424 | 0.82 | ATM (0.44) | ATMKCNA5NPC1RAB9ARXFP1 | |
| SCHEMBL2197313 | 0.82 | TSHR (0.42) | GAAATMCYP3A4PDE10AKCNA5 | |
| SCHEMBL3124272 | 0.81 | ATM (0.39) | GAAATMCYP3A4PDE10AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | GAA 860/4885ATM 3589/4885CYP3A4 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.