Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360204 | 0.95 | MEN1 (0.38) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL12509870 | 0.87 | PDK2 (0.33) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL12424702 | 0.86 | PARP1 (0.35) | PDK2MEN1KMT2AGAAPARP1 | |
| SCHEMBL22005185 | 0.86 | MEN1 (0.34) | PDK2MEN1KMT2AGAA | |
| SCHEMBL13868655 | 0.84 | PDK2 (0.34) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL10293306 | 0.84 | PDK2 (0.34) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL10261681 | 0.84 | PDK2 (0.34) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL24404156 | 0.84 | PDK2 (0.35) | PDK2MEN1KMT2AGAAPARP1 | |
| SCHEMBL12424597 | 0.83 | PDK2 (0.42) | PDK2MEN1KMT2AGAAHSP90AA1 | |
| SCHEMBL13868641 | 0.83 | HDAC4 (0.40) | PDK2MEN1KMT2AGAAHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7976739-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| EP-2055698-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-20100230649-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2055698-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230649-A1 | CHROMENE COMPOUND | CCNT1, RB1, H1-0 | PDK2 1053/4885MEN1 576/4885KMT2A 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.