Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293306 | 1.00 | PDK2 (0.34) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL10292671 | 0.96 | AVPR2 (0.33) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL10261681 | 0.96 | PDK2 (0.34) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL10261395 | 0.95 | AVPR1A (0.36) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL10267872 | 0.93 | MEN1 (0.35) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL10292851 | 0.93 | PDK2 (0.35) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL16301321 | 0.93 | PGAM1 (0.32) | PDK2HDAC4HDAC2HDAC8KMT2A | |
| SCHEMBL13868706 | 0.93 | ALDH1A1 (0.34) | KMT2AMEN1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL10262914 | 0.91 | TTR (0.34) | CYP3A4HPGDMAPT | |
| SCHEMBL10261863 | 0.91 | PDK2 (0.34) | PDK2CYP3A4CYP1A1CYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133211-A1 | PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2023-05-04 | — | — | US | disclosed |
| US-11066523-B2 | Photochromic polyrotaxane compound and curable composition comprising the photochromic polyrotaxane compound | TOKUYAMA CORPORATION (JP) | 2021-07-20 | — | — | US | disclosed |
| EP-3783084-A1 | PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND, AND OPTICAL ARTICLE | Tokuyama Corporation (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-20210032532-A1 | PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND, AND OPTICAL ARTICLE | TOKUYAMA CORPORATION (JP) | 2021-02-04 | — | — | US | disclosed |
| US-20200190106-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING THE COMPOUND, AND OPTICAL ARTICLE INCLUDING A CURED BODY OF THE CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2020-06-18 | — | — | US | disclosed |
| US-20200172681-A1 | PHOTOCHROMIC POLYROTAXANE COMPOUND AND CURABLE COMPOSITION COMPRISING THE PHOTOCHROMIC POLYROTAXANE COMPOUND | TOKUYAMA CORPORATION (JP) | 2020-06-04 | — | — | US | disclosed |
| WO-2019203205-A1 | PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND, AND OPTICAL ARTICLE | 株式会社トクヤマ | 2019-10-24 | — | — | WO | disclosed |
| WO-2019013249-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | 株式会社トクヤマ | 2019-01-17 | — | — | WO | disclosed |
| US-7521004-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7521004-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| EP-1674460-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-20070215844-A1 | Chromene Compound | TOKUYAMA CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070215844-A1 | Chromene Compound | TOKUYAMA CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190106-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING THE COMPOUND, AND OPTICAL ARTICLE INCLUDING A CURED BODY OF THE CURABLE COMPOSITION | INCENP, SMCHD1, ILK | PDK2 3372/4885HDAC4 948/4885HDAC2 1241/4885 |
| US-20070215844-A1 | Chromene Compound | CRY2, TYR, CRY1 | PDK2 893/4885HDAC4 2860/4885HDAC2 879/4885 |
| US-20230133211-A1 | PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND | CRY1, CCNL2, CCNT1 | PDK2 2496/4885HDAC4 1292/4885HDAC2 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.