SCHEMBL12424935

SCHEMBL12424935

COc1c(F)c(F)c(C2=C3C(=O)NC(c4c(F)c(F)c(OC)c(F)c4F)=C3C(=O)N2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.34
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424742 0.81 GRIN2D (0.31)
SCHEMBL12424969 0.74
SCHEMBL12424929 0.73
SCHEMBL1711725 0.71 HSD17B10 (0.47) HSD17B10
SCHEMBL12424915 0.69 CA1 (0.31)
SCHEMBL6833151 0.69 HSD17B10 (0.35) HSD17B10
SCHEMBL12965347 0.69 HSD17B10 (0.45) HSD17B10
SCHEMBL12424881 0.68 STK10 (0.45)
SCHEMBL12425040 0.68 PTGS2 (0.41) HSD17B10
SCHEMBL3763099 0.68 HSD17B10 (0.41) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed