SCHEMBL1242504

SCHEMBL1242504

CCN(CC)c1ccc(/C=C/C=C2c3cc(Br)ccc3-c3ccc(Br)cc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.48
▸ MEN1 O00255 11/20 0.48
▸ KMT2A Q03164 11/20 0.48
▸ ALDH1A1 P00352 10/20 0.48
▸ MAPK1 P28482 7/20 0.48
▸ L3MBTL1 Q9Y468 6/20 0.48
▸ POLB P06746 4/20 0.48
▸ USP2 O75604 3/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ RECQL P46063 2/20 0.48
▸ TLR9 Q9NR96 1/20 0.48
▸ ALDH3A1 P30838 1/20 0.42
▸ ALDH1A3 P47895 1/20 0.42
▸ LMNA P02545 4/20 0.41
▸ GAA P10253 4/20 0.40
▸ THRB P10828 3/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ PKM P14618 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ MDM2 Q00987 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1242502 1.00 MAPT (0.48) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL1242523 0.84 ALDH1A1 (0.49) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL1239938 0.76 MAPT (0.50) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL1239940 0.76 MAPT (0.50) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL2622619 0.75 ALDH1A1 (0.65) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL9351594 0.74 CASP3 (0.43) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL9351590 0.74 CASP3 (0.43) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL2298605 0.71 ALDH1A1 (0.71) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL2298602 0.71 ALDH1A1 (0.71) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL8171054 0.71 ALDH1A1 (0.71) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832616-B1 Pi-conjugated polymer RICOH CO LTD (JP) 2012-10-24 — — EP disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 — — US disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 — — US disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 — — US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
EP-1832616-A1 Pi-conjugated polymer Ricoh Company, Ltd. (JP) 2007-09-12 — — EP disclosed
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