SCHEMBL1242588

SCHEMBL1242588

C=CCCC[Si](C)(C)CCCC=C

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.32
TRPA1 O75762 3/20 0.32
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1241800 0.92 TSHR (0.48) TSHRALDH1A1LMNATRPA1ABCC4
SCHEMBL29236761 0.89 TSHR (0.52) TSHRALDH1A1LMNATRPA1ABCC4
SCHEMBL29236617 0.89 TSHR (0.52) TSHRALDH1A1LMNATRPA1ABCC4
SCHEMBL30890195 0.89 TSHR (0.52) TSHRALDH1A1LMNATRPA1ABCC4
SCHEMBL3673730 0.82
SCHEMBL2954862 0.82 TSHR (0.48) TSHRALDH1A1LMNATRPA1ABCC4
SCHEMBL235272 0.81 TSHR (0.42) TSHRALDH1A1
SCHEMBL4610326 0.81 TSHR (0.70) TSHRALDH1A1ABCC4MAPT
SCHEMBL6063997 0.79 TSHR (0.52) TSHRALDH1A1
SCHEMBL16243604 0.79 TSHR (0.43) TSHRALDH1A1LMNATRPA1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684341-A Double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2025-03-25 CN disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-111433235-B Capped double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2450361-B1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF MITSUI CHEMICALS INC (JP) 2017-10-25 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
US-8791284-B2 Organometallic compound and production method thereof MITSUI CHEMICALS, INC. (JP) 2014-07-29 US disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
EP-2459598-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies LLC (US) 2012-06-06 EP disclosed
EP-2450361-A1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF Mitsui Chemicals, Inc. (JP) 2012-05-09 EP disclosed
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS, INC. 2012-04-26 US disclosed
WO-2011016991-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 TSHR 4645/4885ALDH1A1 2097/4885LMNA 4667/4885
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 TSHR 4812/4885ALDH1A1 3614/4885LMNA 3625/4885
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF SLC39A11, AP2M1, AP1M1 TSHR 3613/4885ALDH1A1 1493/4885LMNA 4509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.