Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509983 | 0.88 | EPHX1 (0.40) | EPHX1MAOAMAOBIDO1MEN1 | |
| SCHEMBL12426963 | 0.85 | APP (0.38) | — | |
| SCHEMBL12426928 | 0.85 | EPHX1 (0.37) | EPHX1MAOAMAOBIDO1MEN1 | |
| SCHEMBL12426942 | 0.85 | EPHX1 (0.37) | EPHX1MAOAMAOBIDO1MEN1 | |
| SCHEMBL2030465 | 0.75 | IDO1 (0.50) | NPC1RAB9AEPHX1MAOBIDO1 | |
| SCHEMBL2201278 | 0.74 | MAOA (0.37) | MAOAMAOBIDO1MEN1KMT2A | |
| SCHEMBL5209430 | 0.64 | MAPT (0.44) | NPC1RAB9AIDO1MEN1KMT2A | |
| SCHEMBL21186074 | 0.64 | EPHX1 (0.39) | NPC1RAB9AEPHX1MAOAMEN1 | |
| SCHEMBL13652552 | 0.64 | IDO1 (0.48) | NPC1RAB9AIDO1MEN1KMT2A | |
| SCHEMBL1145094 | 0.63 | SLC6A4 (0.52) | NPC1RAB9AMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977491-B2 | reacting with ketone compound in presence of solvent | FUJIFILM CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |