SCHEMBL5209430

SCHEMBL5209430

CSCc1ccc(CSC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NOS1 P29475 2/20 0.39
IDO1 P14902 6/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC6A4 P31645 2/20 0.33
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21765871 0.91 HRH3 (0.42) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL10299392 0.88 IDO1 (0.52) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL515186 0.88 MAPT (0.56) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL776074 0.86 LMNA (0.58) NPC1RAB9ALMNAIDO1ALDH1A1
SCHEMBL7658349 0.86 TRPA1 (0.43) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL13534963 0.86 PRSS1 (0.44) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11547033 0.86 ESR1 (0.50) MAPTNPC1RAB9ALMNAKDM4E
SCHEMBL15962378 0.86 LMNA (0.41) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1145094 0.86 SLC6A4 (0.52) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL514209 0.86 ALDH1A1 (0.50) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023150630-A2 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2023-08-10 WO disclosed
WO-2020246571-A1 CELL CULTURE VESSEL PRODUCTION METHOD 株式会社日本触媒 2020-12-10 WO disclosed
WO-2020246572-A1 METHOD FOR RECOVERING CELLS AND/OR AGGREGATES THEREOF 株式会社日本触媒 2020-12-10 WO disclosed
WO-2019030298-A1 NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY ALMIRALL, S.A. (ES) 2019-02-14 WO disclosed
US-7341815-B2 Recording can be effected at a high sensitivity and in which scattering of the recording layer due to ablation is suppressed FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
US-7341815-B2 Recording can be effected at a high sensitivity and in which scattering of the recording layer due to ablation is suppressed FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
EP-1388540-B1 ACRYLIC ESTERS AND USE THEREOF MITSUI CHEMICALS INC (JP) 2007-09-05 EP disclosed
US-7258961-B2 lithographic plates comprising supports having thermosensitive multilayersontaining water-insoluble but alkali-soluble polymer compounds, contain an infrared absorbing dyes, show a broad latitude in development for image formation and can form good images through exposure FUJIFILM CORPORATION (JP) 2007-08-21 US disclosed
US-7258961-B2 lithographic plates comprising supports having thermosensitive multilayersontaining water-insoluble but alkali-soluble polymer compounds, contain an infrared absorbing dyes, show a broad latitude in development for image formation and can form good images through exposure FUJIFILM CORPORATION (JP) 2007-08-21 US disclosed
US-20070099118-A1 lithographic plates comprising supports having thermosensitive multilayersontaining water-insoluble but alkali-soluble polymer compounds, contain an infrared absorbing dyes, show a broad latitude in development for image formation and can form good images through exposure FUJI PHOTO FILM CO., LTD. 2007-05-03 US disclosed
US-20070099118-A1 lithographic plates comprising supports having thermosensitive multilayersontaining water-insoluble but alkali-soluble polymer compounds, contain an infrared absorbing dyes, show a broad latitude in development for image formation and can form good images through exposure FUJI PHOTO FILM CO., LTD. 2007-05-03 US disclosed
US-6835844-B2 Acrylic esters and use thereof MITSUI CHEMICALS, INC. (JP) 2004-12-28 US disclosed
US-20040102592-A1 Acrylic esters and use thereof MITSUI CHEMICALS, INC. (JP) 2004-05-27 US disclosed
EP-1388540-A1 ACRYLIC ESTERS AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2004-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102592-A1 Acrylic esters and use thereof RPS4Y1, EPB41, RPS4X MAPT 4411/4885NPC1 4210/4885RAB9A 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.