Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813528 | 0.89 | — | — | |
| SCHEMBL12047678 | 0.87 | CYP2D6 (0.32) | CYP2D6CYP2C19TSHR | |
| SCHEMBL14012665 | 0.75 | — | — | |
| SCHEMBL13241885 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1TDP1EPHX1 | |
| SCHEMBL18886295 | 0.73 | PRMT1 (0.46) | CYP2D6CYP2C19PRMT1LDHASRR | |
| SCHEMBL23779422 | 0.73 | — | — | |
| SCHEMBL12368562 | 0.71 | — | — | |
| SCHEMBL13156111 | 0.71 | EPHX1 (0.41) | CYP2D6CYP2C19ALDH1A1TSHRGAA | |
| SCHEMBL14703489 | 0.71 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL13029372 | 0.71 | HSD17B10 (0.40) | ALDH1A1TSHRMAPK1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977504-B2 | Process for producing isocyanates and aromatic hydroxy compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | PAH, APEH, HPD | CYP2D6 1584/4885CYP2C19 224/4885ALDH1A1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.