Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10283267 | 0.94 | PRKCA (0.46) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL12427778 | 0.92 | PRKCA (0.44) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL804080 | 0.91 | PRKCA (0.50) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL12427682 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL12427636 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL803839 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL12427734 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL803874 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL803965 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 | |
| SCHEMBL804124 | 0.89 | PRKCA (0.49) | PRKCAMMP12SCN9APRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |