SCHEMBL12428244

SCHEMBL12428244

Cc1ccc(N2CCCc3cc(-c4ccc(/C=C5\C(=O)N(c6ccccc6)N=C5C(=O)O)[nH]4)ccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 6/20 0.41
KAT8 Q9H7Z6 11/20 0.38
SCN9A Q15858 2/20 0.35
MAPT P10636 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428121 0.84 KAT8 (0.45) EP300KAT8MAPTL3MBTL1SMN1; SMN2
SCHEMBL12428202 0.84 KAT8 (0.43) KAT8MAPTL3MBTL1SMN1; SMN2MEN1
SCHEMBL12428249 0.83 EP300 (0.41) EP300KAT8SCN9AMAPTL3MBTL1
SCHEMBL12428248 0.83 SIRT5 (0.47) EP300MAPTL3MBTL1MEN1ALDH1A1
SCHEMBL12428261 0.82 EP300 (0.40) EP300KAT8SCN9AMAPTL3MBTL1
SCHEMBL12428264 0.82 EP300 (0.40) EP300KAT8SCN9AMAPTL3MBTL1
SCHEMBL12428446 0.82 MEN1 (0.42) KAT8SCN9AMAPTL3MBTL1MAPK1
SCHEMBL12428447 0.82 MEN1 (0.42) KAT8SCN9AMAPTL3MBTL1MAPK1
SCHEMBL12428273 0.81 SCN9A (0.36) EP300KAT8SCN9AMAPTL3MBTL1
SCHEMBL12428192 0.81 KAT8 (0.43) KAT8MAPTL3MBTL1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 EP300 2442/4885KAT8 1908/4885SCN9A 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.