SCHEMBL12428372

SCHEMBL12428372

Cc1ccc(N2CCCc3cc(C(=C4C(=O)N(c5ccccc5)N=C4C(=O)O)c4ccc5c(c4)CCCN5c4ccc(C)cc4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 15/20 0.45
OPRK1 P41145 15/20 0.45
OPRD1 P41143 14/20 0.45
ACHE P22303 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KAT8 Q9H7Z6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428121 0.81 KAT8 (0.45) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL12428259 0.81 SCN9A (0.39) OPRM1OPRK1OPRD1ACHEMEN1
SCHEMBL12428197 0.78 KMT2A (0.48) OPRK1MEN1KMT2AALDH1A1LMNA
SCHEMBL12428192 0.77 KAT8 (0.43) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL12428272 0.77 SCN9A (0.36) OPRM1OPRK1OPRD1ACHEMEN1
SCHEMBL12428202 0.77 KAT8 (0.43) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL12428236 0.76 MAPT (0.46) OPRK1MEN1KMT2AALDH1A1LMNA
SCHEMBL12428331 0.76 KMT2A (0.47) OPRK1MEN1KMT2AALDH1A1LMNA
SCHEMBL12428368 0.75 OPRM1 (0.42) OPRM1OPRK1OPRD1ACHEMEN1
SCHEMBL12428249 0.75 EP300 (0.41) ACHEMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 OPRM1 1218/4885OPRK1 2512/4885OPRD1 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.