Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550012 | 0.84 | — | — | |
| SCHEMBL14032355 | 0.81 | TSHR (0.38) | TSHR | |
| SCHEMBL8585590 | 0.79 | — | — | |
| SCHEMBL1712975 | 0.77 | TSHR (0.38) | TSHR | |
| SCHEMBL11704705 | 0.77 | — | — | |
| SCHEMBL10554462 | 0.77 | — | — | |
| SCHEMBL1551559 | 0.77 | — | — | |
| SCHEMBL15463564 | 0.77 | — | — | |
| SCHEMBL11219400 | 0.77 | — | — | |
| SCHEMBL7056732 | 0.76 | TSHR (0.62) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057337-B1 | 4H-BENZO(4,5)CYCLOHEPTA(1,2-B)FURAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | Delbarre, Bernard (FR) | 1984-03-14 | — | — | EP | claimed |
| US-10358419-B2 | 1,3-dipolar [70]fulleropyrrolidinium iodide derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180037548-A1 | 1,3-DIPOLAR [70]FULLEROPYRROLIDINIUM IODIDE DERIVATIVES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-02-08 | — | — | US | disclosed |
| WO-2016145134-A1 | 1,3-DIPOLAR [70]FULLEROPYRROLIDINIUM IODIDE DERIVATIVES | ECHEGOYEN LUIS A (US) | 2016-09-15 | — | — | WO | disclosed |
| EP-2259785-B1 | FULLERENE THERAPIES FOR INFLAMMATION | LUNA INNOVATIONS INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-8680125-B2 | Fullerene therapies for inflammation | LUNA INNOVATIONS INCORPORATED (US) | 2014-03-25 | — | — | US | disclosed |
| US-8563585-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
| US-20110251158-A1 | FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE | LUNA INNOVATIONS INCORPORATED (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110028522-A1 | FULLERENE THERAPIES FOR INFLAMMATION | LUNA INNOVATIONS INCORPORATED (US) | 2011-02-03 | — | — | US | disclosed |
| EP-2259785-A2 | FULLERENE THERAPIES FOR INFLAMMATION | Luna Innovations Incorporated (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009114088-A2 | FULLERENE THERAPIES FOR INFLAMMATION | LUNA INNOVATIONS INCORPORATED (US) | 2009-09-17 | — | — | WO | disclosed |
| US-4383995-A | [4,5] 4H-Benzo [1,2-b] cyclohepta furan derivatives and application thereof as anti-fibrillating agents | DELBARRE B (FR) | 1983-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037548-A1 | 1,3-DIPOLAR [70]FULLEROPYRROLIDINIUM IODIDE DERIVATIVES | CTNND1, INA, CTNNB1 | MGAM 4843/4885GAA 4661/4885SI 4763/4885 |
| US-10358419-B2 | 1,3-dipolar [70]fulleropyrrolidinium iodide derivatives | CTNND1, INA, CTNNB1 | MGAM 4843/4885GAA 4679/4885SI 4771/4885 |
| US-20110251158-A1 | FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE | IL1B, IL1A, CD68 | MGAM 4348/4885GAA 2992/4885SI 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.