Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154534 | 0.86 | CA2 (0.35) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL1154536 | 0.86 | CA2 (0.35) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL12052159 | 0.86 | CA2 (0.35) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL10046784 | 0.77 | PABPC1 (0.36) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL13525222 | 0.75 | PABPC1 (0.36) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL11787610 | 0.75 | PABPC1 (0.41) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL11410974 | 0.74 | PABPC1 (0.39) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL1783165 | 0.74 | MAPT (0.38) | CA2CA12CA9CA7PABPC1 | |
| SCHEMBL1154049 | 0.73 | PABPC1 (0.35) | CA2CA12CA9PABPC1NOS3 | |
| SCHEMBL12052158 | 0.73 | PABPC1 (0.35) | CA2CA12CA9PABPC1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229140-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |