Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10283575 | 0.95 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL803754 | 0.94 | PRKCA (0.42) | PRKCAMMP12DRD3DRD2DRD1 | |
| SCHEMBL10283613 | 0.92 | PRKCA (0.40) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL12427926 | 0.92 | PRKCA (0.41) | PRKCAMMP12DRD3KDM2BSCN9A | |
| SCHEMBL12427983 | 0.92 | PRKCA (0.44) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL12429375 | 0.92 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL12429151 | 0.91 | PRKCA (0.42) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL12428553 | 0.91 | PRKCA (0.43) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL10283578 | 0.91 | PRKCA (0.43) | PRKCAMMP12KDM2BSCN9ANR1I2 | |
| SCHEMBL10283736 | 0.91 | PRKCA (0.43) | PRKCAMMP12KDM2BSCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |